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Masayuki Yoshikawa Selected Research

Experimental Melanoma

6/2019Inhibition of melanin production by anthracenone dimer glycosides isolated from Cassia auriculata seeds.
1/2016Phenylethanoid and phenylpropanoid glycosides with melanogenesis inhibitory activity from the flowers of Narcissus tazetta var. chinensis.
7/2014Dimeric pyrrolidinoindoline-type alkaloids with melanogenesis inhibitory activity in flower buds of Chimonanthus praecox.
4/2014Lignan dicarboxylates and terpenoids from the flower buds of Cananga odorata and their inhibitory effects on melanogenesis.
9/2013Diarylheptanoids with inhibitory effects on melanogenesis from the rhizomes of Curcuma comosa in B16 melanoma cells.
8/2013Acylated sucroses and acylated quinic acids analogs from the flower buds of Prunus mume and their inhibitory effect on melanogenesis.
3/2013Alkaloids from Sri Lankan curry-leaf (Murraya koenigii) display melanogenesis inhibitory activity: structures of karapinchamines A and B.
2/2013Alkaloid constituents from flower buds and leaves of sacred lotus (Nelumbo nucifera, Nymphaeaceae) with melanogenesis inhibitory activity in B16 melanoma cells.
8/2012Melanogenesis inhibitory and fibroblast proliferation accelerating effects of noroleanane- and oleanane-type triterpene oligoglycosides from the flower buds of Camellia japonica.
1/2012Medicinal flowers. XXXVI.1) Acylated oleanane-type triterpene saponins with inhibitory effects on melanogenesis from the flower buds of Chinese Camellia japonica.
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Masayuki Yoshikawa Research Topics

Disease

15Experimental Melanoma
06/2019 - 12/2003
11Leukemia
08/2016 - 03/2006
9Body Weight (Weight, Body)
06/2019 - 07/2002
4Hypersensitivity (Allergy)
01/2016 - 10/2002
2Obesity
06/2021 - 04/2005
2Hyperglycemia
01/2021 - 12/2011
2Neoplasms (Cancer)
12/2018 - 12/2003
2Fibrosarcoma
02/2017 - 02/2007
2Carcinoma (Carcinomatosis)
11/2016 - 07/2016
2Type 2 Diabetes Mellitus (MODY)
02/2015 - 04/2005
2Insulin Resistance
01/2014 - 12/2011
2Hyperlipidemias (Hyperlipidemia)
12/2011 - 04/2005
2Metabolic Syndrome (Dysmetabolic Syndrome X)
12/2011 - 01/2011
1Neuralgia (Stump Neuralgia)
01/2022
1Diabetic Neuropathies (Diabetic Neuropathy)
01/2022
1Dizziness (Lightheadedness)
01/2022
1Neoplasm Metastasis (Metastasis)
01/2019
1Wounds and Injuries (Trauma)
06/2014
1Retinal Diseases
01/2013
1Edema (Dropsy)
07/2011
1Confusion (Bewilderment)
04/2009
1Osteosarcoma (Osteogenic Sarcoma)
10/2007
1Melanoma (Melanoma, Malignant)
03/2006

Drug/Important Bio-Agent (IBA)

14Theophylline (Theon)FDA LinkGeneric
06/2019 - 08/2009
5Blood Glucose (Blood Sugar)IBA
01/2021 - 06/2007
5AntigensIBA
01/2016 - 10/2002
4Hexosaminidases (Hexosaminidase)IBA
08/2016 - 10/2010
4ethyl acetateIBA
03/2013 - 02/2007
4AlkaloidsIBA
02/2013 - 12/2003
3Methanol (Carbinol)IBA
06/2019 - 06/2014
3SaponinsIBA
07/2016 - 10/2011
3FlavonoidsIBA
01/2016 - 10/2002
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
09/2004 - 10/2002
3Interleukin-4 (Interleukin 4)IBA
09/2004 - 10/2002
3Immunoglobulin E (IgE)IBA
09/2004 - 10/2002
2SesquiterpenesIBA
01/2019 - 12/2003
2matrigelIBA
02/2017 - 02/2007
2LipopolysaccharidesIBA
08/2016 - 06/2014
2TriterpenesIBA
07/2016 - 01/2012
2StilbenesIBA
01/2016 - 10/2009
2DiarylheptanoidsIBA
01/2016 - 09/2013
2salacinolIBA
02/2015 - 04/2009
2LipidsIBA
12/2011 - 01/2008
2Glucose (Dextrose)FDA LinkGeneric
12/2011 - 06/2007
2Triglycerides (Triacylglycerol)IBA
12/2011 - 01/2008
2CholesterolIBA
12/2011 - 01/2008
2LuteolinIBA
10/2010 - 10/2002
2AcetoneIBA
08/2009 - 06/2007
1Pregabalin (Lyrica)FDA Link
01/2022
1Analgesics (Analgesic Drugs)IBA
01/2022
1GlucosidasesIBA
01/2021
1gallocatechol (epigallocatechin)IBA
11/2016
1floratheasaponin AIBA
11/2016
1Nitric Oxide (Nitrogen Monoxide)FDA Link
08/2016
1oleananeIBA
07/2016
1Histamine (Histamine Dihydrochloride)FDA Link
01/2016
1Hypoglycemic Agents (Hypoglycemics)IBA
02/2015
1GalactosamineIBA
06/2014
1AdipokinesIBA
01/2014
1Pioglitazone (Actos)FDA Link
01/2014
1Troglitazone (Rezulin)FDA Link
01/2014
1LigandsIBA
01/2014
1ThiazolidinedionesIBA
01/2014
1Peroxisome Proliferator-Activated Receptors (PPAR)IBA
01/2014
1AdiponectinIBA
01/2014
1cyanidinIBA
01/2013
1TunicamycinIBA
01/2013
1Caspase 3 (Caspase-3)IBA
01/2013
1Insulin (Novolin)FDA Link
12/2011
1Fatty Acids (Saturated Fatty Acids)IBA
12/2011
1Neuropeptide YIBA
10/2011
1Capsaicin (Zostrix)FDA Link
10/2011
1Serotonin (5 Hydroxytryptamine)IBA
10/2011
1Messenger RNA (mRNA)IBA
10/2011
1chakasaponin IIIBA
10/2011
1Chloroform (Trichloromethane)IBA
07/2011
1Glucagon-Like Peptide 1 (GLP 1)IBA
01/2011
1TeaIBA
01/2011
1ResveratrolIBA
10/2010
13,3',4,5'-tetrahydroxystilbeneIBA
10/2010
1Actin Depolymerizing Factors (Cofilins)IBA
05/2010
11-Butanol (n Butanol)IBA
05/2010
1Ethanol (Ethyl Alcohol)IBA
05/2010
1cucurbitacin EIBA
05/2010
1benzofuranIBA
10/2009
1beta-N-AcetylhexosaminidasesIBA
10/2009
1PowdersIBA
04/2009
1EmulsionsIBA
01/2008
1cryptolepineIBA
10/2007
1tilirosideIBA
06/2007
1astragalinIBA
06/2007
1p-coumaric acidIBA
06/2007
1kaempferolIBA
06/2007
1deguelinIBA
02/2007
1tephrosinIBA
02/2007
1RotenoneIBA
02/2007
1Pharmaceutical PreparationsIBA
04/2005

Therapy/Procedure

3Oral Administration
12/2011 - 07/2002
1Ayurvedic Medicine (Siddha Medicine)
06/2021
1Drug Therapy (Chemotherapy)
12/2018